Tender, deep lesions are typically found on the legs in patients with erythema nodosum. In erythema nodosum, the areas of skin involved are often red and warm to touch. This image displays multiple red lesions on a leg, typical of erythema nodosum. This image displays the red, elevated areas of the skin on the lower legs, typical of erythema nodosum. This image displays a deep red inflammation typical of erythema nodosum. Erythema nodosum lesions are raised and tender when they begin (early lesions can be seen on the top part of this picture), but older lesions (seen on bottom part of the picture) flatten as they resolve. This image displays red, warm, tender lesions typical of erythema nodosum. This image displays multiple areas of erythema nodosum. This image displays the typical presentation of erythema nodosum on the legs with scattered, red, slightly elevated lesions.
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Erythema Nodosum:
Information for adults

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Picture of Erythema Nodosum: Tender, deep lesions are typically found on the legs in patients with erythema nodosum. Divider line
Tender, deep lesions are typically found on the legs in patients with erythema nodosum.
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Signs and Symptoms
The most common locations for erythema nodosum include:
  • Shins
  • Knees, ankles, or thighs
  • Forearms
  • Face and neck
Erythema nodosum appears as one or more reddish, warm, and painful lumps or nodules, ranging in size from 1–10 cm.

The onset of erythema nodosum may be associated with fever, generalized achiness, leg swelling, or joint pain.

Individual nodules of erythema nodosum usually last from 1–2 weeks, but new lesions may continue to appear for up to 6 weeks. When an individual lesion of erythema nodosum has resolved, it may leave behind a temporary bruise, which subsequently fades to normal-appearing skin.
Last Modified: 1 Feb 2008

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