Oral Melanotic Macule:
Information for adults

If the diagnosis of oral melanotic macule is not certain, your physician may wish to perform a skin biopsy in order to confirm the diagnosis. The procedure involves:

1. Numbing the skin with an injectable anesthetic.
2. Sampling a small piece of skin by using a flexible razor blade, a scalpel, or a tiny cookie cutter (called a "punch biopsy"). If a punch biopsy is taken, a suture or two may be placed and will need to be removed 5–10 days later.
3. Having the skin sample examined under a microscope by a specially trained physician (dermatopathologist).

Your doctor is more likely to biopsy certain lesions, such as new ones, large or growing ones, or those with irregular color (pigmentation). The biopsy can help the doctor to tell whether it is a benign oral melanotic macule or a malignant melanoma, a type of skin cancer.

Most dark spots on the lips or inside the mouth are benign oral melanotic macules. Usually, your doctor will observe the lesion by measuring it, by taking a photograph of it, or both. As long as the oral melanotic macule stays stable in size, shape, and color, no treatment is needed.

Nonetheless, some people want the lesion removed for cosmetic reasons. If it is appropriate, some physicians might recommend excision or, rarely, laser treatment.