Systemic Lupus Erythematosus:
Information for adults

Systemic lupus erythematosus can occur in people of all ages, all races, and both sexes. However, it is far more common in women, especially those between 15–45 years old. In America, it is also more commonly seen in people with darker skin than in light-skinned people.

Although it is not directly inherited, lupus and other autoimmune diseases may run in families. Inheriting certain genes may make some people more susceptible to developing lupus.

In addition, certain environmental factors may trigger lupus in those who have a family (genetic) tendency toward the disease, including:

• Ultraviolet light, especially sunlight
• Certain medications, especially hydralazine and procainamide
• Infections
• Antibiotics, especially penicillins or sulfa-containing medicines
• Stress
• Hormonal changes, especially related to pregnancy and menstrual cycles