Grouped, crusted blisters on the lips and chin are typical of herpes simplex infection. This image displays a blister with a central depression, typical of herpes simplex. The first time a person contracts a herpes infection, there is often severe blistering, pain, and sometimes fever. This image displays an unusual area for the herpes simplex infection. This image displays a mucosal blister caused by a herpes simplex infection. This image displays a herpes simplex infection on the face. This image displays early crusting and swelling typical of recurrent herpes. This image displays multiple grouped herpes lesions that are starting to crust and dry.
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Picture of Cold Sores (Orofacial Herpes): Grouped, crusted blisters on the lips and chin are typical of herpes simplex infection. Divider line
Grouped, crusted blisters on the lips and chin are typical of herpes simplex infection.
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Self-Care Guidelines
Acetaminophen or ibuprofen may help reduce fever, muscle aches, and pain caused by the cold sores. Try to drink as many fluids as possible to prevent dehydration. Applying ice packs may relieve some of the swelling and discomfort. Avoid citrus fruits and juices or spicy foods as they may cause increased pain.

Because herpes simplex virus infections are very contagious, it is important to take the following steps to prevent spread (transmission) of the virus during the prodromal phase (burning, tingling, or itching) and active phase (presence of blisters or sores) of herpes simplex virus infections:
  • Avoid sharing cups or eating utensils.
  • Avoid kissing or performing oral sex.
  • Avoid sharing lip balm or lipstick.
  • Avoid sharing razors, towels, and other personal care items.
  • Wash your hands with soap and water if you touch an active lesion.
Unfortunately, the virus can still be transmitted even when someone does not have active lesions.
When to Seek Medical Care
If you develop tender, painful sores in the mouth or on the lips or nose, see a physician.

Contact your doctor immediately if the outbreak has not gone away in 2 weeks, if you are not eating or drinking because of the pain, or if you develop blisters or sores near your eye.

If you have an underlying medical condition such as cancer or HIV or if you have undergone organ transplantation, you are at higher risk for more serious complications. Seek medical advice as soon as possible, especially if you are at risk for more serious complications.
Last Modified: 29 Jan 2008
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